The Senators forward, who scored a goal and an assist in the win, was one of three Ottawa players using a special edition pink stick in support of the 2nd Annual Tribute to Hockey Moms to raise money for breast cancer research. Dean McAmmond and Wade Redden also used them.
Comrie was just 10-years-old when he lost his mother to breast cancer and the 26-year-old has been an active supporter of the cause for years.
For the second straight year Comrie scored a goal when using the pink stick and joked that he should order a couple dozen with the luck he's had.
"I feel really privileged to be able to raise money for such a great foundation," said Comrie. "Losing my mother was not easy and it's not easy to talk about it, but being in the situation I'm in, I want to do everything I can to help."
Comrie, who had struggled of late, seems to have turned the corner and is playing a much more complete game and earning the praise of coach Bryan Murray.
"(Comrie) is really taking advantage of jumping on loose pucks," said Murray. "He's a sniper and we know he'll be good around the net and (Saturday) he was."
Peter Schaefer and Tom Preissing also scored for the Senators (42-23-7) and Martin Gerber faced 30 shots.
The win allowed the Senators to move ahead of the Pittsburgh Penguins for fourth place in the Eastern Conference standings. The two teams face-off Sunday in Pittsburgh.
Mike Richards and Derian Hatcher scored for the Flyers (20-41-11). Martin Biron stopped 30 shots.
"I think we came in here and played a pretty sound game," said Biron. "We just made a couple of mistakes and they capitalized.
"I think this was a real good test for us. We need to prove we're ready for next season."
The Senators opened the scoring at 14:10 of the first as Preissing, who was left all alone next to the crease, tapped in a rebound by Comrie.
The Flyers tied the game just over a minute later as Richards came from behind the net and was able to bang in the puck as he caught Gerber falling backwards.
Late in the second, Comrie was battling Mike York behind the net, pulled the puck out and beat Biron with a quick shot to give the Senators a 2-1 lead. It marked Comrie's first goal in 13 games.
The game lacked excitement and intensity and the 19,639 on hand at Scotiabank Place deserved credit for their boisterous support.
Hatcher made it a one-goal game scoring on the power play late in the third. It marked his second goal in as many games.
"I think this was huge," said Gerber. "Every point is really valuable when you look at the standings. I think we did a much better job than in some of the previous games."
The victory also allowed Ottawa to sweep the season series over the Flyers 4-0.
The only downside to the game was the Senators inability to capitalize on the power play. Ottawa was 0-for-7 with the man advantage. Dany Heatley also saw his 16-game scoring streak (11-13-24) come to an end.
Notes: Ottawa D Lawrence Nycholat, LW Oleg Saprykin and RW Brian McGrattan were a healthy scratchaThe Flyers were without D Mike Rathje (back, indefinite), LW Simon Gagne (hip, day-to-day) and RW Scottie Upshall (shoulder, indefinite) and G Robert Esche and D Alexandre Picard were a healthy scratch.