Regehr sat out Game 3 of Calgary's opening-round playoff series with Detroit on Tuesday after aggravating a knee injury. The 27-year-old missed the first game of the series but returned for Game 2 on Sunday. He sat out the third period after a collision with Red Wings forward Kris Draper.
Flames coach Jim Playfair hopes to have Regehr back in his lineup for Game 4 on Thursday.
Meanwhile, Red Wings forward Todd Bertuzzi was a game-time decision Tuesday. He's recovering from concussion symptoms and has yet to appear in a game this post-season.